<i>In situ</i> growth of a cobalt porphyrin-based covalent organic framework on multi-walled carbon nanotubes for ultrasensitive real-time monitoring of living cell-released nitric oxide
Yujiao Bai, Jiansong Miao, Xiaodi Bian, Qian Wang, Wenqing Gao, Xue Yu, Guihua Yang, Peihua Zhu, Jinghua Yu
Abstract
) and a low limit of detection (16 nM). Moreover, the biosensor has been successfully used to sensitively monitor NO molecules released from human umbilical vein endothelial cells (HUVECs). This research not only designed a multifunctional intelligent biosensor platform, but also provided a broad prospect for continuous dynamic monitoring of the activity of living cells and their released metabolites.
Topics & Concepts
PorphyrinCovalent bondCarbon nanotubeIn situCobaltOxideNanotechnologyPhotochemistryChemistryMaterials scienceInorganic chemistryOrganic chemistryCovalent Organic Framework ApplicationsLuminescence and Fluorescent MaterialsMetal-Organic Frameworks: Synthesis and Applications