Mechanistic insights into how mixing factors govern polyelectrolyte-surfactant complexation in RNA lipid nanoparticle formulation
Sophia R. Dasaro, Abhishek Singh, Pavlos P. Vlachos, Kurt D. Ristroph
Topics & Concepts
PolyelectrolytePulmonary surfactantNanoparticleChemistryCounterionCationic polymerizationMixing (physics)RNANucleic acidMicelleNanotechnologyChemical engineeringChemical physicsIonMaterials scienceOrganic chemistryBiochemistryAqueous solutionPolymerPhysicsGeneEngineeringQuantum mechanicsRNA Interference and Gene DeliveryPolymer Surface Interaction StudiesAdvanced Polymer Synthesis and Characterization