Lysine methyltransferase SMYD2 enhances androgen receptor signaling to modulate CRPC cell resistance to enzalutamide
Junhong Li, Zhe Hong, Junyu Zhang, Shengfeng Zheng, Fangning Wan, Zheng Liu, Bo Dai
Topics & Concepts
EnzalutamideAndrogen receptorProstate cancerCancer researchMethyltransferaseGene knockdownBiologyDownregulation and upregulationCell growthCell cultureMethylationCancerBiochemistryGeneticsGeneProstate Cancer Treatment and ResearchEpigenetics and DNA MethylationCancer-related gene regulation