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Iron- and cobalt-catalyzed C(sp<sup>3</sup>)–H bond functionalization reactions and their application in organic synthesis

Yungen Liu, Tingjie You, Hai‐Xu Wang, Zhou Tang, Cong‐Ying Zhou, Chi‐Ming Che

2020Chemical Society Reviews206 citationsDOI

Abstract

This review highlights the developments in iron and cobalt catalyzed C(sp<sup>3</sup>)–H bond functionalization reactions with emphasis on their applications in organic synthesis, <italic>i.e.</italic> natural products and pharmaceuticals synthesis and/or modification.

Topics & Concepts

CatalysisCobaltSurface modificationChemistryOrganic synthesisOrganic chemistryPolymer chemistryCombinatorial chemistryPhysical chemistryCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsCyclopropane Reaction Mechanisms
Iron- and cobalt-catalyzed C(sp<sup>3</sup>)–H bond functionalization reactions and their application in organic synthesis | Litcius