Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation

Meri Rogava, Tyler J. Aprati, Wei-Yu Chi, Johannes C. Melms, Clemens Hug, Stephanie H. Davis, Ethan M. Earlie, Charlie Chung, Sachin Kumar Deshmukh, Sharon Wu, George W. Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J. Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T. Gibney, Oliver J. Schmitz, Megan Sykes, Rémi J. Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F. Bakhoum, Semir Beyaz, Lewis C. Cantley, Peter K. Sorger, Sven W. Meckelmann, Alpaslan Tasdogan, David Liu, Ashley M. Laughney, Benjamin Izar