Systemic administration of mesenchymal stem cells loaded with a novel oncolytic adenovirus carrying IL-24/endostatin enhances glioma therapy
Junhe Zhang, Hao Chen, Chen Chen, Haimeng Liu, Yurou He, Junli Zhao, Peiyan Yang, Qinwen Mao, Haibin Xia
Topics & Concepts
Oncolytic virusOncolytic adenovirusGliomaMesenchymal stem cellCancer researchSystemic administrationAdenoviridaeGenetic enhancementEndostatinVirotherapyMedicineBiologyImmunologyIn vivoAngiogenesisPathologyGeneTumor cellsBiochemistryBiotechnologyVirus-based gene therapy researchCAR-T cell therapy researchRNA Interference and Gene Delivery