Deciphering single-cell landscape unravels cell-type-specific functional roles of RNA m<sup>6</sup>A modification in atherosclerosis
Xiaorui Ping, Xiaoyun Liang, Wenlu Xing, Saiqi Wang, Fengcongzhe Gong, Yaqi Cheng, Songqi Duan, Xiongwen Lv, Xueying Li, Tianli Zhang, Chunxiao Chen, Yuxin Zhang, Chengzhu Yuan, Shangyu Liu, Gang Liu, Baofa Sun
Abstract
: Our study provided evidence for the roles of ALKBH5, WTAP and METTL3 in orchestrating atherosclerotic cell-type-specific functions, representing promising targets for precision medicine.
Topics & Concepts
CellRNACell typeChemistryCell biologyComputational biologyBiologyBiochemistryGeneRNA modifications and cancerCardiac tumors and thrombiRNA Research and Splicing