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A versatile strategy to construct free-standing multi-furcated vessels and a complicated vascular network in heterogeneous porous scaffolds <i>via</i> combination of 3D printing and stimuli-responsive hydrogels

Hongxian Su, Qingtao Li, Dingguo Li, Haofei Li, Qi Feng, Xiaodong Cao, Hua Dong

2022Materials Horizons60 citationsDOI

Abstract

inflammatory response. Co-culture of hepatocyte (L02 cells) and human umbilical vein endothelial cells (HUVECs) in HPS-MFVs indicates the successful construction of a liver model. We believe that our method offers a simple and easy-going way to achieve robust fabrication of free-standing multi-furcated blood vessels and prevascularization of porous scaffolds for tissue engineering and regenerative medicine.

Topics & Concepts

Self-healing hydrogelsGelatinMaterials sciencePorosityChitosanNanotechnology3D printingBiomedical engineeringChemical engineeringComposite materialPolymer chemistryChemistryEngineeringOrganic chemistry3D Printing in Biomedical ResearchAdditive Manufacturing and 3D Printing TechnologiesElectrospun Nanofibers in Biomedical Applications
A versatile strategy to construct free-standing multi-furcated vessels and a complicated vascular network in heterogeneous porous scaffolds <i>via</i> combination of 3D printing and stimuli-responsive hydrogels | Litcius