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Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

Mingzhu Yang, Hanwen Yu, Yu Xiu, Shiqi Liang, Yuanlang Hu, Yuxin Luo, Zsuzsanna Izsvák, Chuanbo Sun, Jichang Wang

2022Cell stem cell148 citationsDOI

Topics & Concepts

TotipotentBiologyEmbryonic stem cellCell biologyStem cellGermlineChromatinEmbryoCellular differentiationCell typeGeneticsCellGeneGenomics and Chromatin DynamicsPluripotent Stem Cells ResearchCRISPR and Genetic Engineering
Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells | Litcius