Defective viral RNA sensing linked to severe COVID-19
John W. Schoggins
Abstract
Genetic variation in a sensor of double-stranded RNA can exacerbate COVID-19.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)VirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakRNABiologyComputational biologyMedicineGeneticsGeneOutbreakInternal medicineDiseaseInfectious disease (medical specialty)Viral Infections and Immunology Researchinterferon and immune responsesViral gastroenteritis research and epidemiology