A celastrol-loaded DNA nano-patroller regulates hypothalamus leptin sensitivity and adipose energy expenditure for anti-obesity therapy
Yuhao Liu, Chongmai Zeng, Zhangheng Huang, Weijie Zhuang, Xiangyi Chen, Songhang Li, Zhiqiang Liu, Zhengwen Cai, Jianwei Zhu, Yunfeng Lin
Topics & Concepts
CelastrolLeptinAdipose tissueChemistryInsulin resistanceAppetiteInflammationEndocrinologyObesityInternal medicinePharmacologyMedicineBiochemistryApoptosisNatural Compounds in Disease TreatmentRNA Interference and Gene DeliveryHistone Deacetylase Inhibitors Research