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Quantitative differences between cyclin-dependent kinases underlie the unique functions of CDK1 in human cells

Ho Wai Lau, Hoi Tang, Tsz Kwan Yeung, Man Yee Tam, Danyi Zheng, Siu Ki Chu, Randy Y.C. Poon

2021Cell Reports32 citationsDOIOpen Access PDF

Abstract

-S CDKs in human cells is essentially quantitative.

Topics & Concepts

Cyclin-dependent kinaseCyclin-dependent kinase 1Cell biologyAnaphaseMitosisCyclin BBiologyPolo-like kinaseMitotic exitCyclin ACyclin A2MetaphaseCyclin-dependent kinase 2CytokinesisCell cycleCyclin B1KinaseCyclinGeneticsCellCell divisionProtein kinase AGeneChromosomeMicrotubule and mitosis dynamicsCancer-related Molecular PathwaysPlant nutrient uptake and metabolism