USP18 enhances the resistance of BRAF-mutated melanoma cells to vemurafenib by stabilizing cGAS expression to induce cell autophagy
Zhou-rui Ma, Qianwei Xiong, Shizhong Cai, Lingtao Ding, Chao-hong Yin, Hongliang Xia, Wei Liu, Shu Guang Dai, Yue Zhang, Zhen-hong Zhu, Zhijian Huang, Qian Wang, Xiangming Yan
Topics & Concepts
VemurafenibMelanomaCancer researchAutophagyV600EBiologyGene knockdownMutantCell cultureApoptosisGeneBiochemistryGeneticsMetastatic melanomaUbiquitin and proteasome pathwaysAutophagy in Disease and TherapyMelanoma and MAPK Pathways