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Radical trifluoromethylation

Haiwen Xiao, Zhenzhen Zhang, Yewen Fang, Lin Zhu, Chaozhong Li

2021Chemical Society Reviews413 citationsDOI

Abstract

The trifluoromethyl group plays an increasingly important role in pharmaceuticals, agrochemicals and materials. This tutorial describes recent advances in trifluoromethylation of carbon-centered radical intermediates.

Topics & Concepts

TrifluoromethylationChemistryOrganic chemistryTrifluoromethylAlkylFluorine in Organic ChemistryInorganic Fluorides and Related Compounds
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