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Antidepressant Effects of (S)-Ketamine through a Reduction of Hyperpolarization-Activated Current Ih

Chung Sub Kim, Daniel Johnston

2020iScience17 citationsDOIOpen Access PDF

Abstract

from being increased following CUS, which contributes to the rapid antidepressant effects and resiliency to CUS.

Topics & Concepts

KetamineNMDA receptorAntidepressantPharmacologyChemistryHyperpolarization (physics)AntagonistNeuroscienceReceptorMedicineBiologyHippocampusBiochemistryStereochemistryNuclear magnetic resonance spectroscopyTreatment of Major DepressionTryptophan and brain disordersStress Responses and Cortisol
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