Litcius/Paper detail

Targeting PIM kinases in cancer therapy: An update on pharmacological small-molecule inhibitors

Siwei Chen, Yu‐Shang Yang, Yong Yuan, Bo Liu

2023European Journal of Medicinal Chemistry28 citationsDOIOpen Access PDF

Topics & Concepts

KinasePIM1DruggabilityKinomeAKT2Protein-Serine-Threonine KinasesSerineCancer researchGene silencingSmall moleculePhosphorylationChemistryBiologyBiochemistryProtein kinase AAKT1GeneProtein kinase BCancer Mechanisms and TherapySynthesis and bioactivity of alkaloidsPeptidase Inhibition and Analysis