LHRH conjugated gold nanoparticles assisted efficient ovarian cancer targeting evaluated <i>via</i> spectral photon-counting CT imaging: a proof-of-concept research
Dhiraj Kumar, Mahdieh Moghiseh, Kenny Chitcholtan, Isha Mutreja, Chiara Lowe, Ajeet Kaushik, Anthony Butler, Peter Sykes, Nigel Anderson, Aamir Raja
Abstract
) whereas the MARS SPCCT analysis suggested scattered accumulation of metal around the abdominal cavity. Therefore, the study showed the exciting potential of LHRH conjugated AuNPs to target ovarian cancer and also as a potential contrast agent for novel SPCCT imaging technology.
Topics & Concepts
Conjugated systemColloidal goldMaterials scienceOvarian cancerNanoparticlePhoton countingNanotechnologyBiomedical engineeringPhotonOpticsCancerMedicinePhysicsInternal medicinePolymerComposite materialAdvanced X-ray and CT ImagingNuclear Physics and ApplicationsMachine Learning in Materials Science