Bioinformatics analysis of the differences in the binding profile of the wild-type and mutants of the SARS-CoV-2 spike protein variants with the ACE2 receptor
Muhammad Suleman, Qudsia Yousafi, Javaid Ali, Syed Shujait Ali, Zahid Hussain, Shahid Ali, Muhammad Waseem, Arshad Iqbal, Sajjad Ahmad, Abbas Khan, Yanjing Wang, Dong‐Qing Wei
Topics & Concepts
MutantHydrogen bondDocking (animal)CoronavirusWild typeMolecular dynamicsBinding energyChemistryReceptorBinding sitePlasma protein bindingMoleculeBiophysicsGeneBiologyCoronavirus disease 2019 (COVID-19)BiochemistryComputational chemistryMedicineDiseaseInfectious disease (medical specialty)PhysicsPathologyNuclear physicsOrganic chemistryNursingSARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery MethodsProtein Structure and Dynamics