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Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application

Masanori Kataoka, Takuya Niikawa, Naoya Nagaishi, Tsung-Ling Lee, Alexandre Erler, Julian Savulescu, Tsutomu Sawai

2024European Journal of Cell Biology21 citationsDOIOpen Access PDF

Abstract

This study aims to provide a comprehensive review of the ethical, legal and social issues in human brain organoid research, with a view to different types of research and applications: in vitro research, transplantation into non-human animals, and biocomputing. Despite the academic and societal attention on the possibility that human brain organoids may be conscious, we have identified diverse issues in human brain organoid research and applications. To guide the complex terrain of human brain organoid research and applications, a multidisciplinary approach that integrates ethical, legal, and social perspectives is essential.

Topics & Concepts

OrganoidConsciousnessSocial consciousnessNeuroethicsEthical issuesPsychologyEngineering ethicsCognitive sciencePolitical scienceNeuroscienceLawEngineeringBiomedical Ethics and RegulationNeuroethics, Human Enhancement, Biomedical InnovationsPluripotent Stem Cells Research
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