Daptomycin-Induced Acute Eosinophilic Pneumonia
Gilda M. Portalatin, Jodi-Ann Chin, Brian Foster, K. D. Perry, Carla McWilliams
Abstract
Antibiotic use in pneumonia is a common practice globally when there is suspicion for bacterial involvement. However, there have been few instances where the treatment is the cause of pulmonary symptoms, manifesting as so-called "multifocal pneumonia." Daptomycin is one of the main antibiotics known to have several adverse effects, including drug-induced pulmonary eosinophila. We present the case of a patient with probable daptomycin-induced acute eosinophilic pneumonia. Stopping the offending agent and concomitant steroid therapy resulted in resolution of symptoms and prevention of worsening respiratory distress.
Topics & Concepts
MedicineDaptomycinEosinophilic pneumoniaPneumoniaAntibioticsRespiratory distressIntensive care medicineConcomitantAcute respiratory distressBacterial pneumoniaPulmonary EosinophiliaLungRespiratory diseaseInternal medicineSurgeryStaphylococcus aureusVancomycinBronchoalveolar lavageMicrobiologyBiologyBacteriaGeneticsInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisDrug-Induced Adverse ReactionsPneumonia and Respiratory Infections