Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect
Diego Sbardella, Andrea Coletta, Grazia Raffaella Tundo, Ikhlas M. M. Ahmed, Francesco Bellia, Francesco Oddone, Gianluca Manni, Massimo Coletta
Topics & Concepts
CiticolineAllosteric regulationProteasomeCytidineRegulatorChemistryBiochemistryPharmacologyNeuroscienceCell biologyBiologyBiophysicsEnzymeGeneNeurological Disorders and TreatmentsUbiquitin and proteasome pathwaysRetinoids in leukemia and cellular processes