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CRISPR screens in physiologic medium reveal conditionally essential genes in human cells

Nicholas J. Rossiter, Kimberly S. Huggler, Charles H. Adelmann, Heather R. Keys, Ross Soens, David M. Sabatini, Jason R. Cantor

2021Cell Metabolism151 citationsDOIOpen Access PDF

Topics & Concepts

CRISPRBiologyGeneGenetic screenPhenotypeGeneticsComputational biologyCRISPR and Genetic EngineeringSingle-cell and spatial transcriptomicsGene Regulatory Network Analysis