Click inspired novel pyrazole-triazole-persulfonimide & pyrazole-triazole-aryl derivatives; Design, synthesis, DPP-4 inhibitor with potential anti-diabetic agents
Manisha Nidhar, Shaziya Khanam, Priyanka Sonker, Priya Gupta, Archisman Mahapatra, Swaraj Patil, Brijesh Kumar Yadav, Rahul Kumar Singh, Ashish Kumar Tewari
Topics & Concepts
ChemistryIn vivoClick chemistrySitagliptinIn vitroCatalysisCombinatorial chemistryInhibitory postsynaptic potentialYield (engineering)EnzymeAmino acidStereochemistryChelationActive siteEnzyme inhibitionStructure–activity relationshipBiochemistryLead compound1,2,3-TriazoleTriazoleDiabetes Treatment and ManagementSulfur-Based Synthesis TechniquesClick Chemistry and Applications