Pooling Pharyngeal, Anorectal, and Urogenital Samples for Screening Asymptomatic Men Who Have Sex with Men for Chlamydia trachomatis and Neisseria gonorrhoeae
Duygu Durukan, Tim Read, Catriona S. Bradshaw, Christopher K. Fairley, Deborah A. Williamson, Vesna De Petra, Kate Maddaford, Rebecca Wigan, Marcus Y. Chen, Anne Tran, Eric P. F. Chow
Abstract
Screening for Chlamydia trachomatis and Neisseria gonorrhoeae at the pharyngeal, urogenital, and anorectal sites is recommended for men who have sex with men (MSM). Combining the three individual-site samples into a single pooled sample could result in significant cost savings, provided there is no significant sensitivity reduction. The aim of this study was to examine the sensitivity of pooled samples for detecting chlamydia and gonorrhea in asymptomatic MSM using a nucleic acid amplification test.
Topics & Concepts
Neisseria gonorrhoeaeChlamydia trachomatisGonorrheaAsymptomaticChlamydiaMen who have sex with menGenitourinary systemSexually transmitted diseaseGynecologyMedicineChlamydiaceaeNeisseriaceaeBiologyInternal medicineVirologySyphilisMicrobiologyImmunologyAntibioticsHuman immunodeficiency virus (HIV)Reproductive tract infections researchSyphilis Diagnosis and TreatmentHIV, Drug Use, Sexual Risk