C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation
Deepti Lall, Ileana Lorenzini, Thomas A. Mota, Shaughn Bell, Thomas E. Mahan, Jason D. Ulrich, Hayk Davtyan, Jessica E. Rexach, A.K.M. Ghulam Muhammad, Oksana Shelest, Jesse Landeros, Michael Vazquez, Junwon Kim, Layla Ghaffari, Jacqueline G. O’Rourke, Daniel H. Geschwind, Mathew Blurton‐Jones, David M. Holtzman, Rita Sattler, Robert H. Baloh
Topics & Concepts
NeuroscienceC9orf72MicrogliaAmyloid (mycology)BiologyPsychologyDementiaMedicineInflammationDiseaseInternal medicineFrontotemporal dementiaImmunologyBotanyNeuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatmentsTryptophan and brain disorders