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Practitioner’s Guide to Latent Class Analysis: Methodological Considerations and Common Pitfalls

Pratik Sinha, Carolyn S. Calfee, Kevin Delucchi

2020Critical Care Medicine1,063 citationsDOIOpen Access PDF

Abstract

Latent class analysis is a probabilistic modeling algorithm that allows clustering of data and statistical inference. There has been a recent upsurge in the application of latent class analysis in the fields of critical care, respiratory medicine, and beyond. In this review, we present a brief overview of the principles behind latent class analysis. Furthermore, in a stepwise manner, we outline the key processes necessary to perform latent class analysis including some of the challenges and pitfalls faced at each of these steps. The review provides a one-stop shop for investigators seeking to apply latent class analysis to their data.

Topics & Concepts

Latent class modelProbabilistic latent semantic analysisClass (philosophy)InferenceMedicineCluster analysisData scienceProbabilistic logicData miningMachine learningArtificial intelligenceComputer scienceStatistical Methods and Bayesian InferenceData-Driven Disease SurveillancePneumonia and Respiratory Infections
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