Inhibition of Caspase-1-mediated pyroptosis promotes osteogenic differentiation, offering a therapeutic target for osteoporosis
Hongfeng Ruan, Huihao Zhang, Jing Feng, Huan Luo, Fangda Fu, Sai Yao, Chengcong Zhou, Zhiguo Zhang, Yishan Bian, Hongting Jin, Yuliang Zhang, Chengliang Wu, Peijian Tong, Chengliang Wu, Peijian Tong
Topics & Concepts
PyroptosisRUNX2Cell biologyInflammasomeDownregulation and upregulationOsteopontinMesenchymal stem cellAlkaline phosphataseCaspase 1ChemistryStromal cellCancer researchBiologyImmunologyInflammationGeneBiochemistryEnzymeInflammasome and immune disordersBone Metabolism and DiseasesOsteomyelitis and Bone Disorders Research