Litcius/Paper detail

Design, synthesis and biological evaluation of Schiff’s base derivatives as multifunctional agents for the treatment of Alzheimer’s disease

Jian Shi, Yi Zhou, Keren Wang, Qinge Ma, Rongrui Wei, Qingfeng Li, Yiyang Zhao, Zhanpin Qiao, Shuang Liu, Yumin Leng, Wenmin Liu, Zhipei Sang

2020Medicinal Chemistry Research13 citationsDOI

Topics & Concepts

ChemistryMonoamine oxidaseSchiff baseCombinatorial chemistryLead compoundChelationIC50NeuroprotectionAntioxidantDocking (animal)Drug discoveryPharmacologyIn vitroBiochemistryStereochemistryEnzymeOrganic chemistryMedicineNursingCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsComputational Drug Discovery Methods