ONE-POT SYNTHESIS OF PYRANO[2,3-c]PYRAZOLES USING LEMON PEEL POWDER AS A GREEN AND NATURAL CATALYST
Swati Ghodke, S.U. Tekale, R.D. Pathrikar, Priya M. Khandare, László Kótai, Rajendra P. Pawar
Abstract
A simple one-pot four-component synthesis of pyrano[2,3- c ]pyrazoles has been achieved by the condensation of aldehydes, malononitrile, ethyl acetoacetate and hydrazine hydrate using lemon peel powder as a natural catalyst in ethanol under reflux condition. The advantages of this reaction are less reaction time, high yield, easy availability of the catalyst and green nature of the protocol.
Topics & Concepts
CatalysisLemon juiceChemistryNatural (archaeology)Nuclear chemistryOrganic chemistryBiologySugarPaleontologyMulticomponent Synthesis of HeterocyclesSynthesis and biological activity