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Piezo1-mediated mechanotransduction promotes entheseal pathological new bone formation in ankylosing spondylitis

Siwen Chen, Zihao Li, Dongying Chen, Haowen Cui, Jianru Wang, Zemin Li, Xiang Li, Zhaomin Zheng, Zhongping Zhan, Hui Liu

2022Annals of the Rheumatic Diseases54 citationsDOI

Topics & Concepts

MechanotransductionPIEZO1MedicineCell biologyAnkylosing spondylitisDownregulation and upregulationPI3K/AKT/mTOR pathwaySignal transductionImmunologyCancer researchPathologyBiologyInternal medicineGeneticsReceptorIon channelMechanosensitive channelsGeneErythrocyte Function and PathophysiologySpondyloarthritis Studies and TreatmentsBone Metabolism and Diseases
Piezo1-mediated mechanotransduction promotes entheseal pathological new bone formation in ankylosing spondylitis | Litcius