Development of naringenin-O-carbamate derivatives as multi-target-directed liagnds for the treatment of Alzheimer’s disease
Jing Mi, Ying He, Jing Yang, Yi Zhou, Gaofeng Zhu, Anguo Wu, Wenmin Liu, Zhipei Sang
Topics & Concepts
ChemistryIn vitroLead compoundAntioxidantPharmacologyPotencyChemical synthesisBiochemistryNeuroprotectionStructure–activity relationshipBiological activityPenetration (warfare)In vitro toxicologyCombinatorial chemistryIC50EnzymeCytotoxicityDrugCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsPharmacological Receptor Mechanisms and Effects