Amphiphilic phosphorous dendron micelles co-deliver microRNA inhibitor and doxorubicin for augmented triple negative breast cancer therapy
Liang Chen, Mengsi Zhan, Jin Li, Liu Cao, Huxiao Sun, Régis Laurent, Serge Mignani, Anne‐Marie Caminade, Jean‐Pierre Majoral, Xiangyang Shi
Abstract
. With the proven biocompatibility under the studied doses, the developed amphiphilic phosphorus dendron micelles could be developed as an effective nanomedicine formulation for synergistic cancer therapy.
Topics & Concepts
Triple-negative breast cancerDendrimerDoxorubicinMicelleAmphiphileBreast cancerCancer researchmicroRNACancerMaterials scienceChemotherapyChemistryMedicineInternal medicineOrganic chemistryBiochemistryPolymer chemistryCopolymerPolymerAqueous solutionGeneDendrimers and Hyperbranched PolymersNanoplatforms for cancer theranosticsRNA Interference and Gene Delivery