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Cationic cyclization reactions with alkyne terminating groups: a useful tool in biomimetic synthesis

Olaya García‐Pedrero, Félix Rodríguez

2021Chemical Communications18 citationsDOI

Abstract

Cyclization reactions through cationic intermediates have become a highly valuable tool in organic synthesis. The use of alkynes as the terminating group in this type of cationic process offers wide synthetic possibilities because this group can serve as a precursor of different functionalities. This article shows relevant examples of cationic cyclization reactions with alkynes as terminating groups with the intention of demonstrating the potential of this type of process, particularly in the context of biomimetic synthesis of natural products.

Topics & Concepts

AlkyneCationic polymerizationCombinatorial chemistryChemistryOrganic chemistryCatalysisSynthetic Organic Chemistry MethodsMicrobial Natural Products and BiosynthesisCatalytic Alkyne Reactions
Cationic cyclization reactions with alkyne terminating groups: a useful tool in biomimetic synthesis | Litcius