Unleashing the Power of Bond Cleavage Chemistry in Living Systems
Jie Wang, Xin Wang, Xinyuan Fan, Peng R. Chen
Abstract
reactivation of intracellular proteins. As we embarked on this fruitful progress, we outlined the unmet scientific needs and future directions along this exciting avenue. We believe that the potential of BCRs will be further unleashed when combined with other frontier technologies, such as genetic code expansion and proximity-enabled chemical labeling.
Topics & Concepts
Bioorthogonal chemistryBiomoleculeCleavage (geology)ChemistryNanotechnologyLiving systemsBond cleavageCombinatorial chemistryComputer scienceClick chemistryBiochemistryBiologyMaterials scienceCatalysisFracture (geology)PaleontologyArtificial intelligenceClick Chemistry and ApplicationsChemical Synthesis and AnalysisAdvanced biosensing and bioanalysis techniques