Copper ionophore-autophagy interference nanoregulators for tumor self-defense reprograming to amplify cuproptotic stress and antitumor immunity
Enze Li, Liewei Wen, Caiyun Yin, Nan Wang, Suleixin Yang, Wenzheng Feng, Meiwan Chen
Topics & Concepts
AutophagyATG5ChemistryCell biologyProgrammed cell deathIntracellularImmunogenic cell deathCellular stress responseMitochondrionCellular adaptationCancer researchCancer cellExtracellularPI3K/AKT/mTOR pathwayApoptosisUnfolded protein responseImmune systemKinaseTumor microenvironmentCellBlockadeReactive oxygen speciesProtein kinase BNanoplatforms for cancer theranosticsExtracellular vesicles in diseaseAdvanced Nanomaterials in Catalysis