Visible-light-mediated substituent-controlled regiodivergent (2 + 2)/(3 + 2) cycloadditions for the synthesis of aza-analogs of β-lactam and γ-fused lactam derivatives
Wei‐Fang Zuo, Yang Zhang, Yulin Luo, Xiang Li, Gu Zhan, Jin Zhou, Qiwen Pang, Qian‐Qian Yang, Bo Han
Abstract
Substituent-controlled regiodivergent synthesis of aza-analogs of β-lactam and γ-fused lactam derivatives via the visible-light-induced Wolff rearrangement of α-diazoketones and azo esters.
Topics & Concepts
ChemistryLactamSubstituentStereochemistryCombinatorial chemistryCyclopropane Reaction MechanismsSynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods