MicroRNAs alteration as early biomarkers for cancer and neurodegenerative diseases: New challenges in pesticides exposure
Chiara Costa, Michele Teodoro, Carmela Alessandra Rugolo, Carmela Alibrando, Federica Giambò, Giusi Briguglio, Concettina Fenga
Abstract
many biological pathways through modulation of the expression of target mRNAs. The evaluation of miRNA expression levels may be used to develop new non-invasive strategies for the prediction and prognosis of many diseases, including cancer. However, the application of miRNAs as diagnostic and therapeutic biomarkers in the clinical field is extremely challenging.
Topics & Concepts
microRNABiomarkerCancerDiseaseBiologyMetastasisComputational biologyBiomarker discoveryBioinformaticsDiagnostic biomarkerCancer researchMedicinePathologyProteomicsGeneGeneticsMicroRNA in disease regulationCircular RNAs in diseasesGenomics, phytochemicals, and oxidative stress