The role of SGLT-2 inhibitors in managing type 2 diabetes
Yumiko Tsushima, M. Cecilia Lansang, Vinni Makin
Abstract
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are an exceptionally versatile class of medication, and their glycemic and nonglycemic benefits could help millions of patients with type 2 diabetes. Of note, they have been shown to improve cardiac and renal outcomes, much-needed benefits in patients with type 2 diabetes, who are at a higher risk for developing cardiac and renal dysfunction than those who do not have diabetes. The indications for SGLT-2 inhibitors may continue to expand as ongoing clinical trials provide more insight into these drugs.
Topics & Concepts
MedicineType 2 diabetesDiabetes mellitusGlycemicDapagliflozinClinical trialCanagliflozinIntensive care medicineDrug classInternal medicinePharmacologyEndocrinologyDrugDiabetes Treatment and ManagementPharmacology and Obesity TreatmentPotassium and Related Disorders