Rh(<scp>iii</scp>)-catalyzed substrate-dependent oxidative (spiro)annulation of isoquinolones with diazonaphthoquinones: selective access to new spirocyclic and oxepine-fused polycyclic compounds
Shenghai Guo, Ziyi Zhang, Yuanqing Zhu, Zhaotong Wei, Xinying Zhang, Xuesen Fan
Abstract
An efficient protocol for the selective synthesis of novel isoquinolone-containing spirocyclic and oxepine-fused polycyclic compounds via rhodium( iii )-catalyzed (spiro)annulation of NH -isoquinolones with diazonaphthalen-2(1 H )-ones is reported.
Topics & Concepts
ChemistryAnnulationCatalysisSubstrate (aquarium)Oxidative phosphorylationCombinatorial chemistryStereochemistryOrganic chemistryBiochemistryGeologyOceanographyCatalytic C–H Functionalization MethodsCyclopropane Reaction MechanismsSynthesis and Catalytic Reactions