Identifying conformational changes of aptamer binding to theophylline: A combined biolayer interferometry, surface-enhanced Raman spectroscopy, and molecular dynamics study
Xiaolin Cui, Menghua Song, Yan Liu, Yifan Yuan, Qiang Huang, Yongbing Cao, Feng Lü
Topics & Concepts
AptamerTheophyllineChemistryRaman spectroscopyBiophysicsMolecular dynamicsPharmacologyComputational chemistryMolecular biologyOpticsPhysicsBiologyMedicineAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionGold and Silver Nanoparticles Synthesis and Applications