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Checkpoint Markers and Tumor Microenvironment: What Do We Know?

Ramya Ephraim, Sarah Fraser, Kulmira Nurgali, Vasso Apostolopoulos

2022Cancers30 citationsDOIOpen Access PDF

Abstract

The cancer microenvironment, or tumor microenvironment (TME), describes the non-cancerous cells present in the tumor, such as fibroblasts, immune cells, and cells that comprise the blood vessels and proteins produced by all of the cells present in the tumor that support the growth of the cancer cells [...].

Topics & Concepts

Tumor microenvironmentImmune systemTumor cellsCancer cellCancer researchCancer-Associated FibroblastsCancerBiologyMedicineImmunologyInternal medicineCancer Immunotherapy and BiomarkersCancer Cells and MetastasisFerroptosis and cancer prognosis