A universal allosteric mechanism for G protein activation
Kevin M. Knight, Soumadwip Ghosh, Sharon L. Campbell, Tyler J. Lefevre, Reid H. J. Olsen, Alan V. Smrcka, Natalie Hewitt, Guowei Yin, Nagarajan Vaidehi, Henrik Dohlman
Topics & Concepts
Allosteric regulationBiologyProtein subunitGTP'G proteinBiochemistryGuanosine triphosphateGTPaseCell biologySignal transductionGTP-binding protein regulatorsBiophysicsReceptorEnzymeGeneProtein Kinase Regulation and GTPase SignalingReceptor Mechanisms and SignalingProtein Structure and Dynamics