Metronidazole-induced encephalopathy
Vikash Lala, B Bobat, Mark Haagensen, Prakash Kathan, Adam Mahomed
Abstract
Metronidazole is a widely used antibacterial and antiprotozoal agent for a number of conditions. Whilst its more common gastrointestinal side effects are well known, neurotoxicity remains under-recognised. Both central and peripheral neurological side effects have been described. This report describes a case of radiologically confirmed metronidazole-induced cerebellar ataxia in a cirrhotic patient with a review of the literature. Awareness of this side effect is essential for prompt recognition as early drug withdrawal leads to resolution in the majority of cases.
Topics & Concepts
MedicineMetronidazoleNeurotoxicityAtaxiaEncephalopathySide effect (computer science)DrugEpilepsyAntibioticsGastroenterologyInternal medicinePharmacologyToxicityPsychiatryMicrobiologyProgramming languageComputer scienceBiologyInfectious Encephalopathies and EncephalitisClostridium difficile and Clostridium perfringens researchInfectious Diseases and Tuberculosis