A mixture of chloromethylisothiazolinone and methylisothiazolinone impairs rat vascular smooth muscle by depleting thiols and thereby elevating cytosolic Zn2+ and generating reactive oxygen species
Van Quan, Yoon‐Seok Seo, Jung Min Park, Jieun Yu, Men Thi Hoai Duong, Junichi Nakai, Sang Kyum Kim, Hee‐Chul Ahn, Moo‐Yeol Lee
Topics & Concepts
ChemistryReactive oxygen speciesVascular smooth muscleSuperoxidePharmacologyMedicineBiochemistryInternal medicineSmooth muscleEnzymeAir Quality and Health ImpactsOccupational exposure and asthmaAntimicrobial agents and applications