Protective effects of Erdosteine on interleukin-1β-stimulated inflammation via inhibiting the activation of MAPK, NF-κB, and Wnt/β-catenin signaling pathways in rat osteoarthritis
Xi Yang, Xiaojian Huang, Genmei Tan, Xiangyu Chu, Rui Zhang, Xiaohu Ma, Bowei Ni, Hongbo You
Topics & Concepts
MMP3ChondrocyteIn vivoInflammationOsteoarthritisChemistryMAPK/ERK pathwayProinflammatory cytokineMatrix metalloproteinasePharmacologyInterleukinSignal transductionCytokineEndocrinologyInternal medicineMedicineIn vitroBiologyBiochemistryPathologyGene expressionGeneBiotechnologyAlternative medicineOsteoarthritis Treatment and MechanismsNatural product bioactivities and synthesisInflammatory mediators and NSAID effects