Litcius/Paper detail

Molecular basis for DarT ADP-ribosylation of a DNA base

M. Schuller, Rachel E. Butler, A. Ariza, Callum Tromans‐Coia, Gytis Jankevicius, Timothy D. W. Claridge, Sharon L. Kendall, Shan Goh, Graham R. Stewart, Ivan Ahel

2021Nature79 citationsDOI

Topics & Concepts

BiologyDNADNA repairADP-ribosylationNAD+ kinaseBiochemistryNucleic acidDNA damageEnzymePARP inhibition in cancer therapyDNA Repair MechanismsToxin Mechanisms and Immunotoxins