Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example
Johanna Nyffeler, Clinton Willis, Felix R. Harris, Laura W. Taylor, Richard Judson, Logan J. Everett, Joshua Harrill
Topics & Concepts
Retinoic acidPhenotypeBiologyHigh-throughput screeningTranscriptomeRetinoic acid receptorPhenotypic screeningNonsense-mediated decayGene expression profilingGene expressionCell biologyGeneBiochemistryChemistryRNARNA splicingRetinoids in leukemia and cellular processesMolecular Biology Techniques and ApplicationsCarcinogens and Genotoxicity Assessment