Intrinsic affinity of protein – ligand binding by differential scanning calorimetry
Vaida Linkuvienė, Asta Zubrienė, Daumantas Matulis
Topics & Concepts
ChemistryProtonationEnthalpyDifferential scanning calorimetryLigand (biochemistry)Dissociation constantCarbonic anhydrase IICrystallographyBinding constantProtein ligandIsothermal titration calorimetryLigand efficiencyCarbonic anhydraseStereochemistryBinding sitePhysical chemistryThermodynamicsBiochemistryOrganic chemistryEnzymePhysicsReceptorIonthermodynamics and calorimetric analysesEnzyme function and inhibitionProtein Structure and Dynamics