Lysosomal cholesterol accumulation is commonly found in most peroxisomal disorders and reversed by 2-hydroxypropyl-β-cyclodextrin
Le-Wei Dong, Jian Xiao, Shuai Liu, Gang Deng, Ya-Cheng Liao, Bei‐Bei Chu, Xiaolu Zhao, Bao‐Liang Song, Jie Luo
Topics & Concepts
AdrenoleukodystrophyCholesterolPeroxisomeGene knockdownAdrenal cortexPhenotypeLysosomeIntracellularBiologyChemistryEndocrinologyInternal medicineBiochemistryCell biologyGeneMedicineEnzymePeroxisome Proliferator-Activated ReceptorsCholesterol and Lipid MetabolismLipid metabolism and biosynthesis