CRISPR screen in regulatory T cells reveals modulators of Foxp3
Jessica T. Cortez, Elena Montauti, Eric Shifrut, Jovylyn Gatchalian, Yusi Zhang, Oren Shaked, Yuanming Xu, Theodore L. Roth, Dimitre R. Simeonov, Yana Zhang, Siqi Chen, Zhongmei Li, Jonathan M. Woo, Josephine Ho, Ian Vogel, Grace Y. Prator, Bin Zhang, Youjin Lee, Zhaolin Sun, Igal Ifergan, Frédéric Van Gool, Diana C. Hargreaves, Jeffrey A. Bluestone, Alexander Marson, Deyu Fang
Topics & Concepts
FOXP3Ubiquitin ligaseRegulatorBiologyUbiquitinTranscription factorCell biologyAutoimmunityCancer researchRegulatory T cellImmune systemImmunologyGeneGeneticsT cellIL-2 receptorT-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune Responses